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Mechanism of Circ_HECW2 regulating osteoblast apoptosis in osteoporosis by attenuating the maturation of miR-1224-5p

Abstract Background Osteoporosis (OP) poses a significant clinical challenge with escalating morbidity. This study explores Circ_HECW2 expression in OP patients and its regulatory role in lipopolysaccharide (LPS)-induced osteoblast apoptosis. Methods Circ_HECW2 expression in OP patient serum and hea...

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Principais autores: Chao Zhang, Qiangqiang Li, Zhongduo Ye, Xiong Wang, Hui Zhao, Yongping Wang, Xingxing Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-01-01
coleção:Journal of Orthopaedic Surgery and Research
Assuntos:
Osteoporosis
Circ_HECW2
miR-1224-5p
Osteoblast
Apoptosis
Acesso em linha:https://doi.org/10.1186/s13018-023-04494-x
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