Inherited glutathione reductase deficiency and Plasmodium falciparum malaria--a case study.
In Plasmodium falciparum-infected red blood cells (RBCs), the flavoenzyme glutathione reductase (GR) regenerates reduced glutathione, which is essential for antioxidant defense. GR utilizes NADPH produced in the pentose phosphate shunt by glucose-6-phosphate dehydrogenase (G6PD). Thus, conditions af...
Tallennettuna:
| Päätekijät: | , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science (PLoS)
2009-10-01
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| Sarja: | PLoS ONE |
| Linkit: | http://europepmc.org/articles/PMC2751828?pdf=render |
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