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Hair cortisol as a marker of glucocorticoid replacement adequacy in adrenal insufficiency

BackgroundAchieving physiologic glucocorticoid replacement in adrenal insufficiency (AI) remains challenging, as both under- and over-replacement contribute to morbidity. Hair cortisol concentration (HCC) reflects cumulative cortisol exposure and may provide clinically relevant information beyond si...

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Autores principales: Merve Korkmaz Yilmaz, Semih Tek, Gizem Karatas Kiliccioglu, Aysel Unver Ozkahraman, Mutlu Niyazoglu, Esra Hatipoglu
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2026-04-01
Colección:Frontiers in Endocrinology
Materias:
adrenal insufficiency
biomarker
hair cortisol
hydrocortisone replacement
metabolic outcomes
overreplacement
Acceso en línea:https://www.frontiersin.org/articles/10.3389/fendo.2026.1765179/full
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