Mutating a conserved cysteine in GPIHBP1 reduces amounts of GPIHBP1 in capillaries and abolishes LPL binding

Mutation of conserved cysteines in proteins of the Ly6 family cause human disease—chylomicronemia in the case of glycosylphosphatidylinositol-anchored HDL binding protein 1 (GPIHBP1) and paroxysmal nocturnal hemoglobinuria in the case of CD59. A mutation in a conserved cysteine in CD59 prevented the...

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Detalles Bibliográficos

Principais autores:	Christopher M. Allan, Cris J. Jung, Mikael Larsson, Patrick J. Heizer, Yiping Tu, Norma P. Sandoval, Tiffany Ly P. Dang, Rachel S. Jung, Anne P. Beigneux, Pieter J. de Jong, Loren G. Fong, Stephen G. Young
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2017-07-01
Series:	Journal of Lipid Research
Assuntos:	chylomicrons endothelial cells lipids/chemistry lipolysis and fatty acid metabolism triglycerides glycosylphosphatidylinositol-anchored HDL binding protein 1
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S002222752033594X
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