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Sex dimorphism and tissue specificity of gene expression changes in aging mice

Abstract Background Aging is a complex process that involves all tissues in an organism and shows sex dimorphism. While transcriptional changes in aging have been well characterized, the majority of studies have focused on a single sex and sex differences in gene expression in aging are poorly under...

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Principais autores: Dantong Zhu, Matt Arnold, Brady A. Samuelson, Judy Z. Wu, Amber Mueller, David A. Sinclair, Alice E. Kane
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-10-01
coleção:Biology of Sex Differences
Assuntos:
Mice
Sex dimorphism
Aging
Tissue-specific
Gene expression
Feature selection
Acesso em linha:https://doi.org/10.1186/s13293-024-00666-4
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