Synthesis, Conformational Analysis and Evaluation of the 2-aryl-4-(4-bromo-2-hydroxyphenyl)benzo[1,5]thiazepines as Potential α-Glucosidase and/or α-Amylase Inhibitors

The ambident electrophilic character of the 5-bromo-2-hydroxychalcones and the binucleophilic nature of 2-aminothiophenol were exploited to construct the 2-aryl-4-(4-bromo-2-hydroxyphenyl)benzo[1,5]thiazepines. The structures and conformation of these 2-aryl-4-(4-bromo-2-hydroxyphenyl)benzo[1,5]thia...

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Bibliografske podrobnosti

Principais autores:	Jackson K. Nkoana, Marole M. Maluleka, Malose J. Mphahlele, Richard M. Mampa, Yee Siew Choong
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-10-01
Serija:	Molecules
Teme:	2,3-dihydrobenzo[<i>b</i>][1,5]thiazepines X-ray structure DFT α-glucosidase α-amylase computational studies
Online dostop:	https://www.mdpi.com/1420-3049/27/20/6935
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