Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis

BCL6 corepressor (BCOR) is recurrently mutated in acute myeloid leukaemia and myelodysplastic syndrome. Here, the authors use mouse models to show the mechanism of how inactivation of BCOR in haematopoietic stem cells contributes to the development of leukaemia.

書誌詳細

主要な著者:	Madison J. Kelly, Joan So, Amy J. Rogers, Gareth Gregory, Jason Li, Magnus Zethoven, Micah D. Gearhart, Vivian J. Bardwell, Ricky W. Johnstone, Stephin J. Vervoort, Lev M. Kats
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2019-03-01
シリーズ:	Nature Communications
オンライン･アクセス:	https://doi.org/10.1038/s41467-019-09250-6
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