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Early Transcriptional Changes in Rabies Virus-Infected Neurons and Their Impact on Neuronal Functions

Rabies is a zoonotic disease caused by rabies virus (RABV). As rabies advances, patients develop a variety of severe neurological symptoms that inevitably lead to coma and death. Unlike other neurotropic viruses that can induce symptoms of a similar range, RABV-infected post-mortem brains do not sho...

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Principais autores: Seonhee Kim, Florence Larrous, Hugo Varet, Rachel Legendre, Lena Feige, Guillaume Dumas, Rebecca Matsas, Georgia Kouroupi, Regis Grailhe, Hervé Bourhy
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-12-01
coleção:Frontiers in Microbiology
Assuntos:
rabies virus
transcriptome
early post-infection
matrix protein
neuronal dysfunction
calcium imaging
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmicb.2021.730892/full
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