Marek’s disease virus protein kinase US3 inhibits DNA-sensing antiviral innate immunity via abrogating activation of NF-κB

ABSTRACT Marek’s disease virus (MDV) is an avian alphaherpesvirus associated with Marek’s disease, an immunosuppressive and lymphoproliferative disease in chickens. The DNA sensing pathway mediates innate immune defense against infection by many DNA-containing pathogens, while viruses have evolved m...

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Auteurs principaux:	Kai Li, Rui Liu, Yongzhen Liu, Li Gao, Changjun Liu, Yanping Zhang, Xiaole Qi, Hongyu Cui, Suyan Wang, Yuntong Chen, Yulu Duan, Yulong Gao, Xiaomei Wang
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology 2025-04-01
Collection:	Microbiology Spectrum
Sujets:	Marek’s disease virus US3 innate immunity DNA sensing NF-κB
Accès en ligne:	https://journals.asm.org/doi/10.1128/spectrum.02347-24
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