LncRNA AC006064.4–201 serves as a novel molecular marker in alleviating cartilage senescence and protecting against osteoarthritis by destabilizing CDKN1B mRNA via interacting with PTBP1

Abstract Background Osteoarthritis (OA) is the most prevalent age-related disease in the world. Chondrocytes undergo an age-dependent decline in their proliferation and synthetic capacity, which is the main cause of OA development. However, the intrinsic mechanism of chondrocyte senescence is still...

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Hlavní autoři:	Panyang Shen, Jun Gao, Shaohan Huang, Chenan You, Haitao Wang, Pengyu Chen, Teng Yao, Tianyou Gao, Bohao Zhou, Shuying Shen, Xing Zhao, Jianjun Ma
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-04-01
Edice:	Biomarker Research
Témata:	lncRNAs Osteoarthritis Senescence PTBP1 CDKN1B
On-line přístup:	https://doi.org/10.1186/s40364-023-00477-6
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