TGFβ depletion does neither modulate acute E. coli-induced inflammatory immune responses nor impair the protective effect by chronic filarial infection

TGFβ is an anti-inflammatory molecule that suppresses pro-inflammatory immune responses. Previously, we demonstrated that chronic filarial infection has a beneficial impact on -induced sepsis. In the present study, we investigated whether this protective effect is dependent on TGFβ signaling and whe...

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Библиографические подробности

Главные авторы:	Buerfent, Benedikt C., Ajendra, Jesuthas, Stamminger, Wiebke, Gondorf, Fabian, Hoerauf, Achim, Hübner, Marc P.
Формат:	Artigo
Язык:	Alemão
Опубликовано:	German Medical Science GMS Publishing House 2019-11-01
Серии:	GMS Infectious Diseases
Предметы:	tgf beta sepsis e. coli immune modulation systemic pro-inflammatory response syndrome (sirs) litomosoides sigmodontis helminth filaria nematode
Online-ссылка:	http://www.egms.de/static/en/journals/id/2019-7/id000044.shtml
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