Detecting Selection in the HIV-1 Genome during Sexual Transmission Events

Little is known about whether and how variation in the HIV-1 genome affects its transmissibility. Assessing which genomic features of HIV-1 are under positive or negative selection during transmission is challenging, because very few virus particles are typically transmitted, and random genetic drif...

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書誌詳細

主要な著者:	David Seifert, Beda Joos, Dominique L. Braun, Corinna S. Oberle, Corinne D. Schenkel, Herbert Kuster, Christina Grube, Jürg Böni, Sabine Yerly, Vincent Aubert, Thomas Klimkait, Huldrych F. Günthard, Niko Beerenwinkel, Karin J. Metzner, on behalf of the Swiss HIV Cohort Study
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2022-02-01
シリーズ:	Viruses
主題:	HIV-1 transmission transmitter–recipient pairs Selection Test in Transmission (SeTesT) Vpu ZPHI
オンライン･アクセス:	https://www.mdpi.com/1999-4915/14/2/406
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