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Guided Self-Assembly of ES-Derived Lung Progenitors into Biomimetic Tube Structures That Impact Cell Differentiation

Chemically directed differentiation of pluripotent stem cells (PSCs) into defined cell types is a potent strategy for creating regenerative tissue models and cell therapies. In vitro observations suggest that physical cues can augment directed differentiation. We recently demonstrated that confining...

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Principais autores: John P. Soleas, Linwen Huang, Elisa D’Arcangelo, Maria Cristina Nostro, Thomas K. Waddell, Alison P. McGuigan, Golnaz Karoubi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-12-01
Serier:Bioengineering
Fag:
pluripotent stem cells
lung progenitor cells
geometric confinement
mechanical cue
biomaterial
extracellular matrix
Online adgang:https://www.mdpi.com/2306-5354/8/12/209
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