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Nanographene Oxide Attenuates Acute GVHD by Modulating Macrophage Polarization in a Xenogeneic Mouse Model

Abstract Nanographene oxide (NGO) exhibits immunomodulatory activity and holds promise as a therapeutic agent for graft‐versus‐host disease (GVHD). In a xenogeneic GVHD mouse model, NGO administration improves survival and attenuates pathology with reduced weight loss and leukocyte engraftment, with...

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Principais autores: Aaron Yu, Hyun Sung Park, Dong‐Hoon Chae, Jae Han Park, Jiyoung Heo, Keonwoo Cho, Jiho Kim, Hyewon Lee, Sueyeon Jee, Chanwoo Kim, Soon Won Choi, Jaechul Ryu, Eun‐Hye Hur, Yunsuk Choi, Eun‐Ji Choi, Mi‐Kyung Oh, Hwa‐Yong Lee, Je‐Hwan Lee, Kyung‐Rok Yu
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-12-01
Serier:Advanced Science
Fag:
graft versus host disease
humanized mouse
macrophage
nanographene oxide
nanomedicine
Online adgang:https://doi.org/10.1002/advs.202504569
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