Robust genome and RNA editing via CRISPR nucleases in PiggyBac systems
CRISPR/Cas-mediated genome editing in human pluripotent stem cells (hPSCs) offers unprecedented opportunities for developing in vitro disease modeling, drug screening and cell-based therapies. To efficiently deliver the CRISPR components, here we developed two all-in-one vectors containing Cas9/gRNA...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
KeAi Communications Co., Ltd.
2022-08-01
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| Serie: | Bioactive Materials |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2452199X22000615 |
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