Polyglutamine Ataxias: Our Current Molecular Understanding and What the Future Holds for Antisense Therapies
Polyglutamine (polyQ) ataxias are a heterogenous group of neurological disorders all caused by an expanded CAG trinucleotide repeat located in the coding region of each unique causative gene. To date, polyQ ataxias encompass six disorders: spinocerebellar ataxia types 1, 2, 3, 6, 7, and 17 and accou...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI AG
2021-10-01
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| Series: | Biomedicines |
| Assuntos: | |
| Acceso en liña: | https://www.mdpi.com/2227-9059/9/11/1499 |
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