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The Effects of CSF Neurogranin and APOE ε4 on Cognition and Neuropathology in Mild Cognitive Impairment and Alzheimer’s Disease

Cerebrospinal fluid (CSF) measurements of neurogranin (Ng) have emerged as a promising biomarker for cognitive decline in mild cognitive impairment (MCI) and Alzheimer’s disease (AD). The apolipoprotein E ε4 (APOE ε4) allele is by far the most consistent genetic risk factor for AD. However, it is no...

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Principais autores: Yulan Fan, Ying Gao, Joseph Therriault, Jing Luo, Maowen Ba, Hua Zhang, the Alzheimer’s Disease Neuroimaging Initiative
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2021-04-01
סדרה:Frontiers in Aging Neuroscience
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גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fnagi.2021.667899/full
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