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Exploreing the potential mechanism of Aitongxiao formula inhibiting hepatocellular carcinoma in vitro and in vivo based on network Pharmacology

Abstract To explore the specific effects and potential mechanisms of Aitongxiao Formula (ATXF) in treating HCC. Network pharmacology was first used to predict the potential targets and pathways of ATXF against liver cancer. In vitro and in vivo experiments were conducted to evaluate the effects of A...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Xiaoqing Zhao, Hu Zhou, Meng Xia, Qingqing Cheng, Rongzhi Wang, Junyu Tao, Jing Leng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-07-01
Schriftenreihe:Scientific Reports
Schlagworte:
Aitongxiao formula
HCC
Network Pharmacology
Tumor proliferation
Metastasis
MAPK/ERK sigaling pathway
Online-Zugang:https://doi.org/10.1038/s41598-025-11019-5
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