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Non-linear patterns in age-related DNA methylation may reflect CD4+ T cell differentiation

DNA methylation (DNAm) is an important epigenetic process involved in the regulation of gene expression. While many studies have identified thousands of loci associated with age, few have differentiated between linear and non-linear DNAm trends with age. Non-linear trends could indicate early- or la...

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Autori principali: Nicholas D. Johnson, Howard W. Wiener, Alicia K. Smith, Shota Nishitani, Devin M. Absher, Donna K. Arnett, Stella Aslibekyan, Karen N. Conneely
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis Group 2017-06-01
Serie:Epigenetics
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Accesso online:http://dx.doi.org/10.1080/15592294.2017.1314419
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