Synthesis of a Non-Symmetrical Disorazole C₁-Analogue and Its Biological Activity

The synthesis of a novel disorazole C₁ analogue is described, and its biological activity as a cytotoxic compound is reported. Based on our convergent and flexible route to the disorazole core, we wish to report a robust strategy to synthesize a non-symmetrical disorazole in which we coup...

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Bibliografische Detailangaben

Hauptverfasser:	Luca Lizzadro, Oliver Spieß, Silke Reinecke, Marc Stadler, Dieter Schinzer
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2024-03-01
Schriftenreihe:	Molecules
Schlagworte:	non-symmetrical disorazole convergent synthesis biological activity SAR (structure-activity-relationship)
Online-Zugang:	https://www.mdpi.com/1420-3049/29/5/1123
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