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Correlation between herpes simplex virus neutralizing antibody titers determined by ELVIS cell and traditional plaque reduction assays.

Preventive viral vaccine efficacy trials require large-scale sample analysis to quantitate immune responses and their correlation with infection outcomes. Traditional plaque reduction assays measure a functionally important form of humoral immunity, neutralizing antibody titer. These assays, however...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Tamara P Blevins, Yinyi Yu, Robert B Belshe, Abbie R Bellamy, Lynda A Morrison
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2019-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:https://doi.org/10.1371/journal.pone.0214467
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