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The Effect of Substrate Properties on Cellular Behavior and Nanoparticle Uptake in Human Fibroblasts and Epithelial Cells

The delivery of nanomedicines into cells holds enormous therapeutic potential; however little is known regarding how the extracellular matrix (ECM) can influence cell–nanoparticle (NP) interactions. Changes in ECM organization and composition occur in several pathophysiological states, including fib...

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Principais autores: Mauro Sousa de Almeida, Aaron Lee, Fabian Itel, Katharina Maniura-Weber, Alke Petri-Fink, Barbara Rothen-Rutishauser
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-02-01
Serier:Nanomaterials
Fag:
nanoparticle uptake
extracellular matrix
mechanobiology
nanofibers
stiffness
fibroblasts
Online adgang:https://www.mdpi.com/2079-4991/14/4/342
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