An essential role of the cytoplasmic tail of CXCR4 in G-protein signaling and organogenesis.
CXCR4 regulates cell proliferation, enhances cell survival and induces chemotaxis, yet molecular mechanisms underlying its signaling remain elusive. Like all other G-protein coupled receptors (GPCRs), CXCR4 delivers signals through G-protein-dependent and -independent pathways, the latter involving...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2010-01-01
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| Serier: | PLoS ONE |
| Online adgang: | http://europepmc.org/articles/PMC2988825?pdf=render |
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