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Early life stress exacerbates behavioural and neuronal alterations in adolescent male mice lacking methyl-CpG binding protein 2 (Mecp2)

The methyl-CpG binding protein 2 gene (MECP2) encodes an epigenetic transcriptional regulator implicated in neuronal plasticity. Loss-of-function mutations in this gene are the primary cause of Rett syndrome and, to a lesser degree, of other neurodevelopmental disorders. Recently, we demonstrated th...

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Bibliografiske detaljer
Principais autores: Jose Vicente Torres-Pérez, Elena Martínez-Rodríguez, Anabel Forte, Carlos Blanco-Gómez, Oliver Stork, Enrique Lanuza, Mónica Santos, Carmen Agustín-Pavón
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-08-01
Serier:Frontiers in Behavioral Neuroscience
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Online adgang:https://www.frontiersin.org/articles/10.3389/fnbeh.2022.974692/full
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