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Natural Killer Cell-Secreted IFN-γ and TNF-α Mediated Differentiation in Lung Stem-like Tumors, Leading to the Susceptibility of the Tumors to Chemotherapeutic Drugs

We demonstrate that natural killer (NK) cells induce a higher cytotoxicity against lung cancer stem-like cells (hA549) compared to differentiated lung cancer cell lines (H292). The supernatants from split-anergized NK cells (IL-2 and anti-CD16 mAb-treated NK cells) induced differentiation in hA549....

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Autors principals: Kawaljit Kaur, Angie Perez Celis, Anahid Jewett
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2025-01-01
Col·lecció:Cells
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Accés en línia:https://www.mdpi.com/2073-4409/14/2/90
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