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Immune milieu and microbiome of the distal urethra in Ugandan men: impact of penile circumcision and implications for HIV susceptibility

Abstract Background Coronal sulcus (CS) anaerobe abundance and IL-8 levels are linked to HIV acquisition, and are dramatically reduced after penile circumcision (PC). The distal urethra may be the site of some HIV acquisition before PC, and presumably most acquisition post PC. We describe the immune...

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主要な著者: Ronald M. Galiwango, Daniel E. Park, Sanja Huibner, Abigail Onos, Maliha Aziz, Kelsey Roach, Aggrey Anok, James Nnamutete, Yahaya Isabirye, John Bosco Wasswa, Deo Male, Godfrey Kigozi, Aaron A. R. Tobian, Jessica L. Prodger, Cindy M. Liu, Rupert Kaul
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2022-01-01
シリーズ:Microbiome
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オンライン・アクセス:https://doi.org/10.1186/s40168-021-01185-9
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