Amorphous Solid Dispersions Layered onto Pellets—An Alternative to Spray Drying?

Spray drying is one of the most frequently used solvent-based processes for manufacturing amorphous solid dispersions (ASDs). However, the resulting fine powders usually require further downstream processing when intended for solid oral dosage forms. In this study, we compare properties and performa...

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Autores principales:	Marius Neuwirth, Sebastian K. Kappes, Michael U. Hartig, Karl G. Wagner
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2023-02-01
Colección:	Pharmaceutics
Materias:	amorphous solid dispersions fluid bed spray drying pellet coating supersaturation release kinetics
Acceso en línea:	https://www.mdpi.com/1999-4923/15/3/764
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