Imbalance of stem-like and effector T cell states in children with early type 1 diabetes across conventional and regulatory subsets
Abstract Type 1 diabetes (T1D) is an autoimmune disease caused by the loss of self-tolerance toward insulin-producing pancreatic β-cells. Its etiology remains incompletely understood but involves dysregulated T cell responses. Here, we perform single-cell transcriptomic analysis of peripheral blood...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2025-12-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-025-66459-4 |
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