The Q-junction and the inflammatory response are critical pathological and therapeutic factors in CoQ deficiency

Defects in Coenzyme Q (CoQ) metabolism have been associated with primary mitochondrial disorders, neurodegenerative diseases and metabolic conditions. The consequences of CoQ deficiency have not been fully addressed, and effective treatment remains challenging. Here, we use mice with primary CoQ def...

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Autori principali:	Pilar González-García, María Elena Díaz-Casado, Agustín Hidalgo-Gutiérrez, Laura Jiménez-Sánchez, Mohammed Bakkali, Eliana Barriocanal-Casado, Germaine Escames, Riccardo Zenezini Chiozzi, Franziska Völlmy, Esther A. Zaal, Celia R. Berkers, Albert J.R. Heck, Luis C. López
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2022-09-01
Serie:	Redox Biology
Soggetti:	Coenzyme Q Mitochondrial disease Therapy Omics Phenolic compound
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2213231722001756
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