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Alpha-synuclein pathology enhances peripheral and CNS immune responses to bacterial endotoxins

Increasing evidence points to infectious diseases as contributor to the pathogenesis of neurodegeneration in Parkinson's disease (PD), probably driven by a peripheral and CNS inflammatory response together with alpha-synuclein (aSyn) pathology. Pro-inflammatory lipopolysaccharide (LPS) endotoxin is...

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Kaydedildi:
Asıl Yazarlar: Anna-Sophia Hartke, Cara S. Schreiber, Kristina Lau, Ivo Wiesweg, Inken Waltl, Ulrich Kalinke, Franziska Richter, Christopher Käufer
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2025-02-01
Seri Bilgileri:Neurobiology of Disease
Konular:
Alpha-Synuclein
Parkinson's disease
Lipopolysaccharide
Neurodegenerative disease
Neuroinflammation
Online Erişim:http://www.sciencedirect.com/science/article/pii/S0969996124003759
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