APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease
Abstract Background Aggregation of amyloid β into plaques in the brain is one of the earliest pathological events in Alzheimer’s disease (AD). The exact pathophysiology leading to dementia is still uncertain, but the apolipoprotein E (APOE) ε4 genotype plays a major role. We aimed to identify the mo...
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMC
2020-05-01
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| Edice: | Alzheimer’s Research & Therapy |
| Témata: | |
| On-line přístup: | http://link.springer.com/article/10.1186/s13195-020-00628-z |
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