Local chromatin fiber folding represses transcription and loop extrusion in quiescent cells

A longstanding hypothesis is that chromatin fiber folding mediated by interactions between nearby nucleosomes represses transcription. However, it has been difficult to determine the relationship between local chromatin fiber compaction and transcription in cells. Further, global changes in fiber di...

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Auteurs principaux:	Sarah G Swygert, Dejun Lin, Stephanie Portillo-Ledesma, Po-Yen Lin, Dakota R Hunt, Cheng-Fu Kao, Tamar Schlick, William S Noble, Toshio Tsukiyama
Format:	Artigo
Langue:	Inglês
Publié:	eLife Sciences Publications Ltd 2021-11-01
Collection:	eLife
Sujets:	nucleosome chromatin micro-c transcription condensin quiescence
Accès en ligne:	https://elifesciences.org/articles/72062
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