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Profiling Microglia through Single-Cell RNA Sequencing over the Course of Development, Aging, and Disease

Microglia are macrophages present in the brain that function as the primary and most important source of immune response in the central nervous system (CNS). Regardless of their multitasking role, our knowledge regarding their molecular heterogeneity is limited; due to technical restrictions, it is...

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Autori principali: Spyros Pettas, Korina Karagianni, Eirini Kanata, Athanasia Chatziefstathiou, Nikoletta Christoudia, Konstantinos Xanthopoulos, Theodoros Sklaviadis, Dimitra Dafou
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-08-01
Serie:Cells
Soggetti:
microglia
single-cell RNA sequencing
neurodegenerative diseases
aging
development
disease
Accesso online:https://www.mdpi.com/2073-4409/11/15/2383
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