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Comprehensive Physiologically Based Pharmacokinetic Model to Assess Drug–Drug Interactions of Phenytoin

Regulatory agencies worldwide expect that clinical pharmacokinetic drug–drug interactions (DDIs) between an investigational new drug and other drugs should be conducted during drug development as part of an adequate assessment of the drug’s safety and efficacy. However, it is neither time nor cost e...

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Principais autores: Leyanis Rodriguez-Vera, Xuefen Yin, Mohammed Almoslem, Karolin Romahn, Brian Cicali, Viera Lukacova, Rodrigo Cristofoletti, Stephan Schmidt
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2023-10-01
Serija:Pharmaceutics
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Online dostop:https://www.mdpi.com/1999-4923/15/10/2486
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