Sertoli Cells Improve Myogenic Differentiation, Reduce Fibrogenic Markers, and Induce Utrophin Expression in Human DMD Myoblasts

Duchenne muscular dystrophy (DMD) is an X-linked disease caused by mutations in <i>DMD</i> gene translating in lack of functional dystrophin and resulting in susceptibility of myofibers to rupture during contraction. Inflammation and fibrosis are critical hallmarks of DMD muscles, which undergo prog...

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Principais autores:	Laura Salvadori, Sara Chiappalupi, Iva Arato, Francesca Mancuso, Mario Calvitti, Maria Cristina Marchetti, Francesca Riuzzi, Riccardo Calafiore, Giovanni Luca, Guglielmo Sorci
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2021-10-01
叢編:	Biomolecules
主題:	duchenne muscular dystrophy (DMD) Sertoli cell utrophin heregulin β1 myoblast differentiation fibrosis
在線閱讀:	https://www.mdpi.com/2218-273X/11/10/1504
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