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Association of iron metabolism with disease severity in acute Puumala hantavirus infection

Abstract Background Serum ferritin is associated with disease severity in haemorrhagic fevers caused by various viruses, while iron has been implicated in the development of acute kidney injury (AKI). Puumala hantavirus causes a haemorrhagic fever with renal syndrome with acute kidney injury (AKI),...

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Principais autores: Johanna Tietäväinen, Tuula Outinen, Ulla Nivukoski, Outi Laine, Satu Mäkelä, Heini Huhtala, Onni Niemelä, Ilkka Pörsti, Antti Vaheri, Jukka Mustonen
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-12-01
Serier:BMC Nephrology
Fag:
Puumala hantavirus
Acute kidney injury
Iron
Ferritin
Hepcidin
Neutrophil-gelatinase associated lipocalin
Online adgang:https://doi.org/10.1186/s12882-025-04609-y
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