The influence of concomitant proton pump inhibitors use on treatment efficacy in hepatocellular carcinoma patients receiving immune checkpoint inhibitors: a systematic review and meta-analysis

BackgroundDespite the significant survival benefit offered by immune checkpoint inhibitors (ICIs) in patients with hepatocellular carcinoma (HCC), a subset of patients still develop drug resistance. Recent evidence suggests that proton pump inhibitors (PPIs) may influence the therapeutic efficacy of...

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Bibliografische gegevens

Hoofdauteurs:	Yangfei Duan, Qitai Zhao, Shumin Feng, Wei Jing, Dan Wang, Yi Zhang
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Frontiers Media S.A. 2026-02-01
Reeks:	Frontiers in Immunology
Onderwerpen:	hepatocellular carcinoma immune checkpoint inhibitors overall survival progression-free survival proton pump inhibitors
Online toegang:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1717420/full
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