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Initial colony morphology-based selection for iPS cells derived from adult fibroblasts is substantially improved by temporary UTF1-based selection.

BACKGROUND: Somatic cells can be reprogrammed into induced pluripotent stem (iPS) cells. Recently, selection of fully reprogrammed cells was achieved based on colony morphology reminiscent of embryonic stem (ES) cells. The maintenance of pluripotency was analysed. METHODOLOGY/PRINCIPAL FINDINGS: Clo...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Kurt Pfannkuche, Azra Fatima, Manoj K Gupta, Rebecca Dieterich, Jürgen Hescheler
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2010-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC2833193?pdf=render
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