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MSK-Mediated Phosphorylation of Histone H3 Ser28 Couples MAPK Signalling with Early Gene Induction and Cardiac Hypertrophy

Heart failure is a leading cause of death that develops subsequent to deleterious hypertrophic cardiac remodelling. MAPK pathways play a key role in coordinating the induction of gene expression during hypertrophy. Induction of the immediate early gene (IEG) response including activator protein 1 (A...

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Hoofdauteurs: Emma L. Robinson, Faye M. Drawnel, Saher Mehdi, Caroline R. Archer, Wei Liu, Hanneke Okkenhaug, Kanar Alkass, Jan Magnus Aronsen, Chandan K. Nagaraju, Ivar Sjaastad, Karin R. Sipido, Olaf Bergmann, J. Simon C. Arthur, Xin Wang, H. Llewelyn Roderick
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2022-02-01
Reeks:Cells
Onderwerpen:
cardiomyocyte
MSK
phosphorylated histone 3 serine 28
immediate early genes
hypertrophy
Online toegang:https://www.mdpi.com/2073-4409/11/4/604
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