Cortical and basal ganglia beta oscillations and frequency-dependent DBS effects in the A53T Parkinson’s disease rat model

Abstract Parkinson’s disease (PD) is a movement disorder characterized by alpha-synuclein (a-Syn) aggregation, dopaminergic degeneration, and pathological beta oscillations (13–30 Hz) in the basal ganglia circuit. Deep brain stimulation (DBS) is an effective neurosurgical treatment for the motor sym...

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Autors principals:	Laura Kondrataviciute, Minesh Kapadia, Ivan Skelin, Srdjan Sumarac, Luka Zivkovic, Luis Antonio Franco Vergara, Sabika Jafri, Cherisse Tan, Hien Chau, Yuhan Hou, Savanna Blade, Xilin Liu, Clement Hamani, Taufik Valiante, William D. Hutchison, Luka Milosevic, Lorraine V. Kalia, Suneil K. Kalia
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2026-03-01
Col·lecció:	npj Parkinson's Disease
Accés en línia:	https://doi.org/10.1038/s41531-026-01304-z
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