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Connexin37‐Dependent Mechanisms Selectively Contribute to Modulate Angiotensin II‐Mediated Hypertension

Background Gap junction channels made of Connexin37 (Cx37) are expressed by aortic endothelial and smooth muscle cells of hypertensive mice, as well as by the renin‐secreting cells of kidneys. Methods and Results To decipher whether Cx37 has any role in hypertension, angiotensin II (Ang II) was infu...

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Principais autores: Loïc Le Gal, Maxime Pellegrin, Tania Santoro, Lucia Mazzolai, Armin Kurtz, Paolo Meda, Charlotte Wagner, Jacques‐Antoine Haefliger
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2019-04-01
coleção:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Assuntos:
angiotensin II
aorta
connexins
endothelial cells
hypertension
kidney
Acesso em linha:https://www.ahajournals.org/doi/10.1161/JAHA.118.010823
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