DNase γ is the effector endonuclease for internucleosomal DNA fragmentation in necrosis.
Apoptosis and necrosis, two major forms of cell death, can be distinguished morphologically and biochemically. Internucleosomal DNA fragmentation (INDF) is a biochemical hallmark of apoptosis, and caspase-activated DNase (CAD), also known as DNA fragmentation factor 40 kDa (DFF40), is one of the maj...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS ONE |
| Acceso en liña: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24312463/pdf/?tool=EBI |
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