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In silico design and development of benzyl piperazine conjugates for targeting choline esterase pathway in Alzheimer's disease

Alzheimer’s disease (AD) is projected to affect 150 million people by 2050 due to global aging. As no cure currently exists and the disease progressively worsens, there is an urgent need for disease-modifying agents capable of restoring cognitive function. The current study aims to identify novel le...

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Главные авторы: Amuthalakshmi Sivaperuman, Keerthana Dhanabalan, Ramalakshmi Natarajan, Nalini Calambur Nagarajan, Dhatchana Moorthy Nachiappan, Viswas Raja Solomon
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2026-01-01
Серии:In Silico Research in Biomedicine
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Online-ссылка:http://www.sciencedirect.com/science/article/pii/S3050787126001447
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