Constructing chimeric mouse islets to study alpha- and delta-cell influence on beta-cell feature

Objectives: This study aimed to evaluate the role of alpha- and delta-cell signals on beta-cells within pancreatic mouse islets. Specifically, we investigated how these signals regulate glucose sensitivity, gene expression and function in beta-cells. Methods: We first implemented our previous protoc...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Alexis Fouque, Masaya Oshima, Nina Mode, Romain Ducellier, Delphine Thibaut, Florence Gbahou, Latif Rachdi, Over Cabrera, Raphaël Scharfmann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-11-01
coleção:	Molecular Metabolism
Assuntos:	Pancreas Islets Endocrine cells Chimeric clusters Insulin secretion
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2212877825001528
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!