Astrocytes from P301S Tau mice exhibit non-canonical protein secretion and reduced morphological complexity

Astrocytes have important neurosupportive functions in the brain that are altered in neurodegenerative diseases by unresolved mechanisms. We showed previously that astrocytes cultured from mice transgenic for human P301S-tau (P301S-mice) recapitulate the deficit in production and secretion of thromb...

Descripció completa

Dades bibliogràfiques

Autors principals:	Aishwarya G. Nadadhur, Matthew Mason, Johanna S. Rees, Marta Sidoryk-Wegrzynowicz, Aviva M. Tolkovsky, Maria Grazia Spillantini
Format:	Artigo
Idioma:	Inglês
Publicat:	Wolters Kluwer Medknow Publications 2026-07-01
Col·lecció:	Neural Regeneration Research
Matèries:	astrocyte conditioned medium basal metabolism extracellular matrix nerve regeneration neuronal survival p301s tau transgenic mice structural maturation tau tauopathy unconventional secretion
Accés en línia:	https://journals.lww.com/10.4103/NRR.NRR-D-24-01598
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!