Effect of Insertion and Deletion in the Meq Protein Encoded by Highly Oncogenic Marek’s Disease Virus on Transactivation Activity and Virulence

Marek’s disease virus (MDV) causes malignant lymphoma in chickens (Marek’s disease, MD). Although MD is currently controlled by vaccination, MDV strains have continuously increased in virulence over the recent decades. Polymorphisms in Meq, an MDV-encoded oncoprotein that serves as a transcription f...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Jumpei Sato, Shiro Murata, Zhiyuan Yang, Benedikt B. Kaufer, Sotaro Fujisawa, Hikari Seo, Naoya Maekawa, Tomohiro Okagawa, Satoru Konnai, Nikolaus Osterrieder, Mark S. Parcells, Kazuhiko Ohashi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-02-01
Schriftenreihe:	Viruses
Schlagworte:	Marek’s disease virus Marek’s disease Meq CVI988 tumorigenesis pathogenicity
Online-Zugang:	https://www.mdpi.com/1999-4915/14/2/382
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!