Validation of high-throughput oxford nanopore technology for HIV-1 transmitted/founder virus identification

HIV-1 Transmitted/Founder (T/F) viruses cause 80-90% of heterosexual transmissions, making their rapid identification vital for vaccine and cure development. Single-genome amplification (SGA) followed by Sanger sequencing is the gold standard for T/F virus detection, but low throughput and high cost...

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Hlavní autoři:	Drake Byamukama, Christian Ndekezi, Denis Omara, Angella Nakyanzi, Fortunate Natwijuka, Frank Kato, Susan Mugaba, Magambo Phillip Kimuda, Anne Kapaata, Eunice Nduati, Pontiano Kaleebu, Sheila Nina Balinda
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-12-01
Edice:	International Journal of Infectious Diseases
Témata:	Oxford Nanopore Technology HIV-1 Transmitted/Founder Viruses Single-Genome Amplicons
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S1201971225003601
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