Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity.

While oxidative stress has been linked to Alzheimer's disease, the underlying pathophysiological relationship is unclear. To examine this relationship, we induced oxidative stress through the genetic ablation of one copy of mitochondrial antioxidant superoxide dismutase 2 (Sod2) allele in mutant hum...

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Detalhes bibliográficos

Principais autores:	Hyun-Pil Lee, Neel Pancholi, Luke Esposito, Laura A Previll, Xinglong Wang, Xiongwei Zhu, Mark A Smith, Hyoung-gon Lee
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2012-01-01
coleção:	PLoS ONE
Acesso em linha:	https://doi.org/10.1371/journal.pone.0028033
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