Discovery of vina-ginsenoside R18 as a novel dual-target inhibitor of dengue virus envelope protein and RNA-dependent RNA polymerase

Dengue virus (DENV) poses a serious health threat globally for which specific antivirals are not available. Envelope (E) protein and RNA-dependent RNA polymerase (RdRp) from DENV represent the most critical targets for the development of antivirals that inhibit viral adsorption for entry and genome...

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Hlavní autoři:	Xuemei He, Yuanru Zheng, Lifang Zou, Jingtao Yu, Bing Chen, Zhuolin Guo, Gefei Peng, Zibin Lu, Wei Zhao, Jianping Zuo, Fen Ouyang, Linzhong Yu, Junshan Liu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Compuscript Ltd 2025-11-01
Edice:	Acta Materia Medica
Témata:	dengue virus envelope protein rna-dependent rna polymerase target inhibitor
On-line přístup:	https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0094
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