A disintegrin and metalloproteinase with thrombospondin motifs 4-targeted molecular magnetic resonance imaging for early detection of extracellular matrix remodeling in a porcine model of abdominal aortic aneurysm

ABSTRACT: Background: Abdominal aortic aneurysm (AAA) progression is driven by extracellular matrix (ECM) proteolysis and vascular smooth muscle cell loss, processes insufficiently captured by diameter-based surveillance. A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4) is...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Marie-Luise H.H. Ranner-Hafferl, Dilyana B. Mangarova, Jennifer L. Heyl, Jennifer Mein, Jana Möckel, Dirk Schnapauff, Timo A. Auer, Federico Collettini, Lisa C. Adams, David Hingst, Jan O. Kaufmann, Marcus R. Makowski, Uwe Karst, Bernd Hamm, Julia Brangsch, Avan Kader
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2026-01-01
Schriftenreihe:	Journal of Cardiovascular Magnetic Resonance
Schlagworte:	ADAMTS4 Protein Aortic Aneurysm, Abdominal Extracellular Matrix Magnetic Resonance Imaging Molecular Imaging Swine
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S1097664726000360
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